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82 PROCEEDINGS OF INTERNATIONAL SCIENTIFIC CONFERENCE ON APPLIED BIOTECHNOLOGY400 %u00b5g/mL, both studied compounds were associated with the SC values of more than 65%. The SC values were decreased in the line with decreases in the tested concentrations. As a consequence, compounds 1-2 showed strong antioxdative activity the IC50values of 33.23 %u00b1 0.03 and 38.41 %u00b1 0.05 mg/mL, compared with that of the standard ascorbic acid (IC50 = 10.38 %u00b1 0.01 mg/mL).Table 1. The DPPH radical scavenging of flavonoids 1 - 2No. Concentration (%u00b5g/mL) Scavenging capacity (SC, %)1400 67.11 %u00b1 0.04200 55.24 %u00b1 0.0.2100 50.3 %u00b1 0.0350 34.12 %u00b1 0.0325 9.21 %u00b1 0.01IC50 = 33.23 %u00b1 0.03 mg/mL2400 65.56 %u00b1 0.01200 59.31 %u00b1 0.02100 45.11 %u00b1 0.0550 19.29 %u00b1 0.0425 5.98 %u00b1 0.02IC50 = 38.41 %u00b1 0.05 mg/mLAscorbic acid IC50 = 10.38 %u00b1 0.01 mg/mLAntioxidative and immunomudulatory activities of green propolis might be due to the presence of flavonoids. Another flavonoids from green propolis, namely quercetin 3-methyl ether and 3,3%u2019-O-dimethylquercetin acted as scavengers with the corresponding IC50 values of 12.4 and 16.23 %u00b5g/mL [11]. The immunomodulatory action of caatinga propolis and its constituents at noncytotoxic concentrations, specifically an antiinflammatory activity in lipopolysaccharide (LPS)-treated cells by inhibiting cytokine production [12].