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SECTION I: MOLECULAR GENETIC ENGINEERING AND BIOCHEMICAL TECHNOLOGY 109HO fraction. Both fractions demonstrated significant antiinflammatory effects, with IC50 values of 40.99 %u00b5g/mL (LO) and 49.44 %u00b5g/mL (HO), although less potent than the positive control, L-NMMA (IC50 = 4.08 %u00b5g/mL). GC-MS analysis of the LO fraction identified 26 volatile compounds, with 1,8-Cineole as the predominant constituent (57%), alongside cis-sabinene hydrate acetate, %u03b1-Pinene, trans-Isosafrole, and %u03b3-Terpinene. These findings suggest that 1,8-Cineole plays a critical role in the observed bioactivities. The study highlights the therapeutic potential of C. camphora essential oils and lays a foundation for further exploration of their bioactive components.Keywords: Cinnamomum camphora, Essential oil, Antioxidant activity, Anti-inflammatory activity, 1,8-Cineole, GC-MS analysis1. INTRODUCTIONThe traditional herbal bath remedy using medicinal plants from the Red Dao ethnic group in Northwest Vietnam is a valuable part of the region%u2019s cultural and medical heritage. This method is widely known for its benefits in alleviating bone and joint pain, with particular relevance for postpartum women. Rheumatoid arthritis (RA), which often manifests as joint pain, muscle weakness, and potential long-term joint damage, is notably affected by climate, worsening in colder weather-a condition that is especially prevalent among the elderly, according to the World Health Organization (WHO). Managing RA generally requires ongoing treatment involving various medications, as it cannot be completely cured. Patients on medication are advised to return for regular follow-ups every 1-2 months for dosage adjustments to mitigate potential side effects [1].