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104 PROCEEDINGS OF INTERNATIONAL SCIENTIFIC CONFERENCE ON APPLIED BIOTECHNOLOGY4. CONCLUSIONSThe current study describes chemical and biological analyses for S. oreodoxa leaf oil. By the GC/FID-MS technique, the obtained oil was determined to contain monoterpene derivatives (96.2%) as the main chemical class. This result matches well with previous reports, in which %u03b1-pinene, myrtenyl acetate, and %u03b2-pinene were the principal compounds. The studied oil showed good antimicrobial activity, especially in terms of inhibition of bacteria S. aureus and E. faecalis. Three main compounds, %u03b1-pinene, myrtenyl acetate, and %u03b2-pinene have been further submitted to a docking study with target proteins of bacteria S. aureus (3WQU) and E. faecalis (2WE5). It can be seen from the docking results that myrtenyl acetate is more efficient. This compound demonstrated that it operated on numerous important binding sites, and has antibacterial properties. The in silico ADMET analysis revealed non-toxic property of the major compounds.Conflicts of Interest: The authors declare no conflict of interestREFERENCES1. Sam, N.L.; Sovanmoly, H.; Jana, L.S. Siliquamomum oreodoxa (Zingiberaceae): a new species from Southern Vietnam. Gard. Bull. Singapore 2010, 61, 359-368.2. Jana, L.S.; Dang, H.T.; Binh, Q.N.; %u0160%u00edda, O. Siliquamomum alcicorne (Zingiberaceae: Alpinioideae), a new species from central Vietnam. Gard. Bull. Singapore 2014, 66, 39-46.3. Truong, H.L.; Dang, H.T.; Toan, N.T.; Hoan, V.N.; Binh, N.P. Siliquamomum phamhoangii, a new species of Zingiberaceae from the central highlands, Vietnam. Phytotaxa 2017, 314, 135.