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396 PROCEEDINGS OF INTERNATIONAL SCIENTIFIC CONFERENCE ON APPLIED BIOTECHNOLOGYhas been the focus of research and application by various scholars[2-6]. Numerous studies in biotechnology have demonstrated that root-associated microorganisms and endophytes effectively restore the biological health of agricultural soils [3,7,8]. Notably, combining these with biotechnological products containing nitrogen-fixing microbes, phosphate-solubilizing bacteria, plant growth-promoting rhizobacteria, or pest-suppressing microorganisms provides significant advantages for soil management and crop productivity [9].This paper presents some research results on the application of multifunctional biological products for improving degraded soil used for peanuts in Quang Tri Province. 2. MATERIALS AND METHODS 2.1. Sample collectionThe biological products developed for soil improvement consist of various beneficial microbial strains. These include three bacterial strains: Bacillus subtilis TiN1, Bacillus megaterium CFB3, and Bacillus flexus Ti6; two fungal strains such as Penicillium oxalicum N19CL and Trichoderma harzianum N4.1; and one actinobacterial strain as Streptomyces diastatochromogenes CL%u0110 XK3. These strains were developed as part of the pilot production projects VAST.N%u0110P.14/12-13, VAST.SXTN.04/15-16, and KHCN-TN3/11-15. Additionally, two bacterial strains, Nitrosomonas winogradski NBRC 14297 and Azotobacter chroococcum NBRC 102613, were produced using submerged and surface fermentation technologies at the Quang Tri Research, Technology Transfer, and Innovation Center. The project employs the peanut cultivar Sen Lai and utilizes a method of composting agricultural by-products with selected microorganisms to produce microbial organic fertilizer. The research and application of these techniques are scheduled from January 2024 to May 2024.