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SECTION I: MOLECULAR GENETIC ENGINEERING AND BIOCHEMICAL TECHNOLOGY 257been observed, probiotics are currently considered more as a supportive treatment method rather than a primary treatment for mental health conditions.Conflicts of Interest: The authors declare no conflict of interest. REFERENCES1. Mental health in Viet Nam. Available online: https://www.who.int/vietnam/health-topics/mental-health (Accessed on 01 December 2024).2. Khokhlova E, Colom J, Simon A, et al. Immunomodulatory and antioxidant properties of a novel potential probiotic Bacillus clausii CSI08. Microorganisms 2023; vol. 11, no. 2, p. 240. 3. Majeed M, Nagabhushanam K, Arumugam S, Majeed S, Ali F. Bacillus coagulans MTCC 5856 for the management of major depression with irritable bowel syndrome: a randomised, double-blind, placebo controlled, multi-centre, pilot clinical study. Food Nutr Res 2018, vol. 62, p. 10.29219.4. Xu Y, Yu Y, Shen Y, et al. Effects of Bacillus subtilis and Bacilluslicheniformis on growth performance, immunity, short chain fatty acid production, antioxidant capacity, and cecal microflora in broilers. Poult Sci 2021, vol. 100, no. 9, p. 101358.5. Paynich ML, Jones-Burrage SE, Knight KL. Exopolysaccharide from Bacillus subtilis induces anti-inflammatory M2 macrophages that prevent T cell%u2013mediated disease. The Journal of Immunology 2017, vol. 198, no. 7, pp. 2689%u20132698.6. Iloba I, McGarry S V., Yu L, Cruickshank D, Jensen GS. Differential immune-modulating activities of cell walls and secreted metabolites from probiotic Bacillus coagulans JBIYZ6.3 under normal versus inflamed culture conditions. Microorganisms 2023, vol 11, no.10, p.2564.