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SECTION I: MOLECULAR GENETIC ENGINEERING AND BIOCHEMICAL TECHNOLOGY 57REFERENCES1. Edmunds A.J.F.; True, W.; Oppolzer, W.; Cowley, P. Herboxidiene: Determination of absolute configuration by degradation and synthetic studies. Tetrahedron. 1997, 53, 2785-2802.2. Piper, V.; Libby E.W.; Cummings, D.;Nathan, T.; Foundation, C.; Trautman, P.J. Herboxidiene : A Potent Phytotoxic Polyketide from Streptomyces Utilization of NMR Techniques in the Structure. 1992, 57,7220-7226.3. Miller-Wideman M, Makkar N, Tran M, Isaac B, Biest N, Stonard R. Herboxidiene, a new herbicidal substance from streptomyces chromofuscus a7847 taxonomy, fermentation, isolation, physico-chemical and biological properties.J. Antibiot. (Tokyo) 1992, 45, 914-921.4. Shao, L.; Zi, J.; Zeng, J.; Zhan J. Identification of the herboxidiene biosynthetic gene cluster in Streptomyces chromofuscus ATCC 49982. Appl. Environ. Microbiol. 2012, 78, 2034-2038.5. Hopwood, D.A. Cracking the polyketide code. PLoS Biol.2004, 2, e35.6. Pokhrel, A.R.; Dhakal, D.; Jha, A.K.; Sohng, J.K. Herboxidiene biosynthesis, production, and structural modifications: prospect for hybrids with related polyketide. Appl. Microbiol. Biotechnol. 2015, 99, 8351-8362.7. Hertweck, C. The biosynthetic logic of polyketide diversity. Angew. Chemie - Int. Ed. 2009, 48, 4688%u20134716.8. Yadav, G.; Gokhale, R.S.; Mohanty, D. Towards Prediction of Metabolic Products of Polyketide Synthases: An In Silico Analysis. PLoS Comput. Biol. 2009, 5, e1000351.9. Berkhan, G.; Merten, C.; Holec, C.; Hahn, F. The Interplay between a Multifunctional Dehydratase Domain and a