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SECTION I: MOLECULAR GENETIC ENGINEERING AND BIOCHEMICAL TECHNOLOGY 207extract from Streptomyces bingchenggensis ULS14 was toxic to all tested cell lines [5]. In the Morrope and Bayovar salt lagoons of northwestern Peru, bacteria belonging to the genera Streptomyces, Pseudonocardia, Staphylococcus, Bacillus, and Pseudomonas were identified; and the majority of the genus Actinobacteria. Of these, three strains belonging to the genus Streptomyces, MW562814, MW562805, and MW562807, showed antiproliferative activities against three tumor cell lines: U251 glioma, MCF-7 (breast adenocarcinoma), and NCI-H460 (large cell lung cancer); and antibacterial activity against multidrug-resistant Staphylococcus aureus ATCC 6538, Escherichia coli ATCC 10536, and Acinetobacter baumannii AC-972 [6]. Among the three bacterial strains with anti-pathogen and cancer cell toxicity activity isolated from Nai Lagoon, Ninh Thuan province, we identified 2/3 strains belonging to the genus Bacillus, and one strain belonging to the genus Acinetobacter. Currently, there are very few studies on biologically active microorganisms from lagoon environments in the world, and new studies only focus on actinomycetes. There is no domestic research on this issue, so we have not been able to compare the results of this study with other studies in Vietnam and worldwide. However, there have been many studies showing the antibacterial, antifungal, and cancer cell inhibitory activities of species of the genus Bacillusisolated from the marine environment. For example, according to Pournejati and Karbalaei-Heidari (2018), about 15.4% of bacterial strains isolated from the Iranian coast of the Persian Gulf were capable of producing antibacterial substances against S. aureusand P. aeruginosa, while the genus Bacillus had the most potential [15]. Galaviz-Silva et al. (2018) also reported acute antibacterial activity against food poisoning strains of Staphylococcus aureus and Vibrio parahaemolyticus by Bacillus aerius, B. oryzicola, B. safensis, B.