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94 PROCEEDINGS OF INTERNATIONAL SCIENTIFIC CONFERENCE ON APPLIED BIOTECHNOLOGYLogP, hydrogen bond donors, hydrogen bond acceptors, and molar refractivity [17]. This evaluation is performed using the %u201cSupercomputing Facility for Bioinformatics and Computational Biology%u201d web server at IIT Delhi (http://www.scfbio-iitd.res.in/software/drugdesign/lipinski.jsp) [18]. Additionally, the oral toxicity of the selected compounds has been assessed using the ProTox web server [19].3. RESULTS AND DISCUSSIONHydro-distillation of the fresh leaves gave a yellow oil with a yield of 0.16% v/w. By the GC/FID-MS analysis, a total of 26 compounds were identified, which accounted for 98.6% (Table 1 and Figure S1). The obtained oil was dominated by monoterpene hydrocarbons (62.2%, 9 compounds) and their oxygenated derivatives (34.0%, 13 compounds). Sesquiterpene hydrocarbons (2.4%, 4 compounds) are the next chemical class found in this oil. %u03b1-Pinene (34.4%), myrtenyl acetate (20.7%), and %u03b2-pinene (17.3%) can be seen as the principal compounds. Some compounds have reached significant amounts, including limonene (5.7%), linalool (4.5%), myrtenol (2.4%), %u03b1-terpineol (1.8%), sabinyl acetate (1.6%), o-cymene (1.3%), %u03b2-selinene (1.3%), %u03b3-terpinene (1.1%), and camphene (1.0%). As mentioned above, %u03b1-pinene and %u03b2-pinene were also the major compounds in S. tonkinense leaf essential oil [4]. Our current result matches well with previous reports since %u03b1-pinene and %u03b2-pinene can be seen as the main compounds of S. oreodoxa leaf and rhizome oils [6,7]. So far, it can be safely concluded that these two isomers are likely to be the main compounds in Vietnamese Siliquamomum essential oils. The obtained oil has been further subjected to antimicrobial examination. As shown in Table 2, S. oreodoxa leaf essential oil with the MIC value of 16-128 %u00b5g/mL was better than streptomycin in antimicrobial assay against Gram (+) bacteria E. faecalis and S. aureus.