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SECTION II. APPLIED BIOTECHNOLOGY IN THE PHARMACEUTICAL INDUSTRY... 409The results of this study also show that the model applying multifunctional biological products for soil improvement, supplemented with beneficial microbial strains, has supported increased height of peanut plants, enhanced the number of effective flowers, increased the total number of pods per plant, boosted the number of sound pods, and raised the weight of 100 pods, leading to a 22% increase in yield. Earlier, a study by Nguyen Thu Ha et al. (2016) [4] using microbial products on peanuts grown in coastal sandy soils in Nghe An and Binh Dinh provinces resulted in yield increases of 16.1% to 18.2%.By understanding and managing the interactions between soil, plants, and beneficial microorganisms, biotechnology offers effective tools to enhance soil fertility, reduce environmental impact, and promote the goals of sustainable agriculture. 5. CONCLUSIONSThe application of 5 kg/ha of multifunctional biological products for soil improvement in the fertilization and care process of peanuts in Quang Tri Province has resulted in an increase in soil acidity (pHKCl) from 3.97 to 4.67; the organic carbon content (OC%) increased from 2.78% to 6.89%. The available phosphorus and potassium contents, initially at 197.52 mg/100g and 206.68 mg/100g, respectively, increased to 439.53 mg/100g and 511.60 mg/100g. The calcium content (Ca++) rose from 7.73 Idl/100g to 8.76 Idl/100g, and magnesium (Mg++) increased from 1.55 Idl/100g to 2.42 Idl/100g. Notably, the density of beneficial microorganisms, nitrogenfixing microorganisms, phosphate-solubilizing microorganisms, and cellulose-decomposing microorganisms all increased after 4 months of fertilization, rising from 1,92x106, 2,64x105, 4,48x105, 3,55x105 to 6,86x106, 1,45x106, 2,04x106 v%u00e0 1,71x106, respectively. This supports a 22% increase in peanut yield, with a profit of 54,870,000 VND achieving a profit margin of 1.61 times.